Whole-genome screening

Screen 1000+ diseases with one swab.

Sequence your entire genome, decoded and explorable. Ask questions, see your disease risks, and learn what makes you you. Significant findings belong in a clinician conversation.

1000+ conditions screened

Know what towatch, early.

We sequence your entire genome at 30x depth and surface over 2,000 signals across disease risk, carrier status, and medication response, each tied to the exact gene behind it and written in plain language.

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UrgentSee a clinician soonMonitorKeep an eye on itTraitGood to know

A single test.Endless health context.

Included with the health analysis

Genetic risk signals across common hereditary and cancer-related conditions.

  • Breast cancer
  • Colorectal cancer
  • Gastric cancer
  • Male breast cancer
  • Ovarian cancer
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HealthPreviewClinician notes

Health summary

Your genome analysis

Complete

Hereditary risk

2

review now

Medication

7

drug notes

Clinician notes

12

topics

Top findings

Cancer risk review

Discuss confirmatory testing

Medication response

CYP2C19 guidance available

Carrier insight

Partner comparison supported

Included in your test

From swab to sequenced insights.

One purchase covers the physical collection kit, 30x whole-genome sequencing, and the health analysis layer that makes the data useful.

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Genome package

What you get

Part 1

Test kit

30x

whole genome sequencing

Cheek swab collection
Prepaid return mailer
Clinical-grade sample handling

Part 2

Health analysis

6+

report categories

Health reports
Pharmacogenomics
Clinician-ready context

More DNA means better insights.

Manuscript Genomics
100% of your DNA
Other tests

1,000x

more DNA sequenced than typical genotyping tests.

One test.A lifetime of context.

Manuscript Genomics sends a collection kit to your home, sequences your genome at 30x, and turns the result into health analysis you can discuss with a clinician.

  • Cheek swab kit
  • 30x sequencing
  • Health analysis included
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Manuscript Genomics whole-genome sequencing collection kit

See why people choose whole-genome analysis.

Maya C.

I finally had a single place to understand my genetic risk signals without guessing what every variant meant.

David M.

The medication section gave me a concrete list to bring to my doctor before starting a new prescription.

Sarah K.

The value was not just the first report. It was having a clearer way to discuss my genome over time.

Jordan E.

A full genome test felt abstract until the health analysis made it obvious what was actionable.

Nina P.

It gave me a calmer way to sort what mattered now from what I could simply keep watching.

Marcus R.

The carrier and heart-health sections made the report feel concrete enough to discuss with my family.

Elena G.

I liked that the analysis did not pretend every variant was urgent. It gave context.

Owen B.

The report gave me language I could bring into a clinician visit without pretending I had all the answers.

Invest in your future.

What could cost you $1,299+ for $599.

Open Manuscript Genomics whole-genome sequencing collection kit with swabs and sample tube
Manuscript covers
Manuscript
Cost on your own*
Cancer screening
$300
Carrier screening
$449
Heart screening
$300
Neurology screening
$250
Total cost
$599
$1,299
Order my test
Free shippingAt-home collectionHealth analysis included

Genome package

Order Manuscript Genomics.

Today

$599

A single purchase covers the at-home kit, 30x whole-genome sequencing, and account access for the health analysis experience.

At-home cheek swab kit
30x whole-genome sequencing
Plain-language health analysis
Account access for results

After checkout

1

Order placed

Account and shipping details captured

2

Kit shipped

Collection kit sent to the customer

3

Results account

AI guide available after reports are ready

Secure checkout

Package total: $599

Stripe will collect payment, phone number, and US shipping details on the next step.

Clinical-grade reporting requires appropriate physician order and signature. Lab data is investigational use only until reviewed through the required clinical process.

How it works

1+

Swab your cheek

2+

Send your sample

3+

Get your results

Questions? Answers.

What's included?

Your Manuscript Genomics kit includes cheek swabs, a collection tube, a prepaid return mailer, and clear instructions for completing the test at home. The purchase also includes 30x whole-genome sequencing and plain-language educational health analysis.

What will my results tell me?

Your results summarize genetic risk signals across 3,000+ screenings, with context for how DNA, family history, and lifestyle factors can shape health risk over time.

Is Manuscript Genomics available internationally?

Shipping availability depends on the country. The checkout experience can support approved regions and route unsupported countries to a waitlist as more locations are added.

Can I use my results with my clinician?

Yes. Manuscript is designed to help you understand what to watch, discuss, and follow up on with a qualified clinician. Reports are educational decision support, not a diagnosis.

How do I collect my DNA sample?

Collection is designed around a simple cheek swab that you can complete at home, then send back using the included prepaid return mailer.

Your data is secure, private, and always under your control.

Learn more about our commitments

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